Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes

In chronologically aging yeast, longevity can be extended by administering a caloric restriction (CR) diet or some small molecules. These life-extending interventions target the adaptable target of rapamycin (TOR) and cAMP/protein kinase A (cAMP/PKA) signaling pathways that are under the stringent c...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Goldberg, Alexander A., Richard, Vincent R., Kyryakov, Pavlo, Bourque, Simon D., Beach, Adam, Burstein, Michelle T., Glebov, Anastasia, Koupaki, Olivia, Boukh-Viner, Tatiana, Gregg, Christopher, Juneau, Mylène, English, Ann M., Thomas, David Y., Titorenko, Vladimir I.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2010
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933888/
https://ncbi.nlm.nih.gov/pubmed/20622262
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items