Specific changes in mitochondrial lipidome alter mitochondrial proteome and increase the geroprotective efficiency of lithocholic acid in chronologically aging yeast

We have previously found that exogenously added lithocholic acid delays yeast chronological aging. We demonstrated that lithocholic acid enters the yeast cell, is sorted to mitochondria, resides in both mitochondrial membranes, changes the relative concentrations of different membrane phospholipids,...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncotarget
Päätekijät: Leonov, Anna, Arlia-Ciommo, Anthony, Bourque, Simon D., Koupaki, Olivia, Kyryakov, Pavlo, Dakik, Pam鼳la, McAuley, M鼳lissa, Medkour, Younes, Mohammad, Karamat, Maulo, Tamara Di, Titorenko, Vladimir I.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Impact Journals LLC 2017
Aiheet:
Research Paper: Gerotarget (Focus on Aging)
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458158/
https://ncbi.nlm.nih.gov/pubmed/28410198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16766
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