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Taltirelin is a superagonist at the human thyrotropin-releasing hormone receptor
Taltirelin (TAL) is a thyrotropin-releasing hormone (TRH) analog that is approved for use in humans in Japan. In this study, we characterized TAL binding to and signaling by the human TRH receptor (TRH-R) in a model cell system. We found that TAL exhibited lower binding affinities than TRH and lower...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3466466/ https://ncbi.nlm.nih.gov/pubmed/23087672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2012.00120 |
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