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Taltirelin is a superagonist at the human thyrotropin-releasing hormone receptor

Taltirelin (TAL) is a thyrotropin-releasing hormone (TRH) analog that is approved for use in humans in Japan. In this study, we characterized TAL binding to and signaling by the human TRH receptor (TRH-R) in a model cell system. We found that TAL exhibited lower binding affinities than TRH and lower...

詳細記述

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書誌詳細
主要な著者: Thirunarayanan, Nanthakumar, Raaka, Bruce M., Gershengorn, Marvin C.
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466466/
https://ncbi.nlm.nih.gov/pubmed/23087672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2012.00120
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