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Persistent signaling by thyrotropin-releasing hormone receptors correlates with G-protein and receptor levels

G-protein-coupled receptors with dissociable agonists for thyrotropin, parathyroid hormone, and sphingosine-1-phosphate were found to signal persistently hours after agonist withdrawal. Here we show that mouse thyrotropin-releasing hormone (TRH) receptors, subtypes 2 and 1(TRH-R2 and TRH-R1), can si...

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Библиографические подробности
Главные авторы: Boutin, Alisa, Allen, Michael D., Neumann, Susanne, Gershengorn, Marvin C.
Формат: Artigo
Язык:Inglês
Опубликовано: Federation of American Societies for Experimental Biology 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405277/
https://ncbi.nlm.nih.gov/pubmed/22593547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-207860
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