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PGC-1 Proteins and Heart Failure
The transcriptional co-activators PGC-1α and PGC-1β are master regulators of oxidative phosphorylation and fatty acid oxidation gene expression. Pressure overload hypertrophy and heart failure are associated with repressed PGC-1α and PGC-1β gene expression. Maintaining expression of PGC-1α and β pre...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3466400/ https://ncbi.nlm.nih.gov/pubmed/22939990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcm.2012.07.003 |
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