Regulation of fatty acid metabolism by mTOR in adult murine hearts occurs independently of changes in PGC-1α

Mechanistic target of rapamycin (mTOR) is essential for cardiac development, growth, and function, but the role of mTOR in the regulation of cardiac metabolism and mitochondrial respiration is not well established. This study sought to determine cardiac metabolism and mitochondrial bioenergetics in...

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Autores principales: Zhu, Yi, Soto, Jamie, Anderson, Brandon, Riehle, Christian, Zhang, Yi Cheng, Wende, Adam R., Jones, Deborah, McClain, Donald A., Abel, E. Dale
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2013
Materias:
Energetics and Metabolism
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727103/
https://ncbi.nlm.nih.gov/pubmed/23624629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00877.2012
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