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Ablation of PGC1 beta prevents mTOR dependent endoplasmic reticulum stress response
Mitochondria dysfunction contributes to the pathophysiology of obesity, diabetes, neurodegeneration and ageing. The peroxisome proliferator-activated receptor-gamma coactivator-1β (PGC-1β) coordinates mitochondrial biogenesis and function as well as fatty acid metabolism. It has been suggested that...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Academic Press
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3549498/ https://ncbi.nlm.nih.gov/pubmed/22771762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2012.06.031 |
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