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mTOR is a critical regulator of cardiac hypertrophy in Spontaneously Hypertensive Rats

Evidence exists that protein kinase c (PKC) and the mammalian target of rapamycin (mTOR) are important regulators of cardiac hypertrophy. We examined the contribution of these signaling kinases to cardiac growth in Spontaneously Hypertensive Rats (SHR). Systolic blood pressure (mmHg) was increased (...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Soesanto, Will, Lin, Han-yi, Hu, Eric, Lefler, Shane, Litwin, Sheldon E., Sena, Sandra, Abel, E. Dale, Symons, J. David, Jalili, Thunder
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2803027/
https://ncbi.nlm.nih.gov/pubmed/19884565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.109.138818
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