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Increased memory differentiation is associated with decreased polyfunctionality for HIV but not for CMV-specific CD8+ T cells

The generation of polyfunctional CD8+ T cells, in response to vaccination or natural infection, has been associated with improved protective immunity. However, it is unclear whether the maintenance of polyfunctionality is related to particular cellular phenotypic characteristics. To determine whethe...

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書誌詳細
主要な著者: Riou, Catherine, Treurnicht, Florette, Abrahams, Melissa-Rose, Mlisana, Koleka, Liu, Michael K.P., Goonetilleke, Nilu, Koup, Richard, Roederer, Mario, Karim, Salim Abdool, de Bruyn, Guy, Williamson, Carolyn, Gray, Clive M., Burgers, Wendy A.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466366/
https://ncbi.nlm.nih.gov/pubmed/22966086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201488
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