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Increased memory differentiation is associated with decreased polyfunctionality for HIV but not for CMV-specific CD8+ T cells
The generation of polyfunctional CD8+ T cells, in response to vaccination or natural infection, has been associated with improved protective immunity. However, it is unclear whether the maintenance of polyfunctionality is related to particular cellular phenotypic characteristics. To determine whethe...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3466366/ https://ncbi.nlm.nih.gov/pubmed/22966086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201488 |
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