Conserved positive selection signals in gp41 across multiple subtypes and difference in selection signals detectable in gp41 sequences sampled during acute and chronic HIV-1 subtype C infection

BACKGROUND: The high diversity of HIV variants driving the global AIDS epidemic has caused many to doubt whether an effective vaccine against the virus is possible. However, by identifying the selective forces that are driving the ongoing diversification of HIV and characterising their genetic conse...

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Bibliographic Details
Main Authors: Bandawe, Gama P, Martin, Darren P, Treurnicht, Florette, Mlisana, Koleka, Karim, Salim S Abdool, Williamson, Carolyn
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630941/
https://ncbi.nlm.nih.gov/pubmed/19025632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-5-141
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