Limited Neutralizing Antibody Specificities Drive Neutralization Escape in Early HIV-1 Subtype C Infection

We previously showed that HIV-1 subtype C viruses elicit potent but highly type-specific neutralizing antibodies (nAb) within the first year of infection. In order to determine the specificity and evolution of these autologous nAbs, we examined neutralization escape in four individuals whose respons...

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Main Authors: Moore, Penny L., Ranchobe, Nthabeleng, Lambson, Bronwen E., Gray, Elin S., Cave, Eleanor, Abrahams, Melissa-Rose, Bandawe, Gama, Mlisana, Koleka, Abdool Karim, Salim S., Williamson, Carolyn, Morris, Lynn
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2009
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742164/
https://ncbi.nlm.nih.gov/pubmed/19763271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000598
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