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The Mitochondrial Na(+)/Ca(2+) Exchanger Upregulates Glucose Dependent Ca(2+) Signalling Linked to Insulin Secretion

Mitochondria mediate dual metabolic and Ca(2+) shuttling activities. While the former is required for Ca(2+) signalling linked to insulin secretion, the role of the latter in β cell function has not been well understood, primarily because the molecular identity of the mitochondrial Ca(2+) transporte...

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Detalhes bibliográficos
Main Authors: Nita, Iulia I., Hershfinkel, Michal, Fishman, Daniel, Ozeri, Eyal, Rutter, Guy A., Sensi, Stefano L., Khananshvili, Daniel, Lewis, Eli C., Sekler, Israel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466326/
https://ncbi.nlm.nih.gov/pubmed/23056385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046649
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