NCLX is an essential component of mitochondrial Na(+)/Ca(2+) exchange

Mitochondrial Ca(2+) efflux is linked to numerous cellular activities and pathophysiological processes. Although it is established that an Na(+)-dependent mechanism mediates mitochondrial Ca(2+) efflux, the molecular identity of this transporter has remained elusive. Here we show that the Na(+)/Ca(2...

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Detalhes bibliográficos
Main Authors: Palty, Raz, Silverman, William F., Hershfinkel, Michal, Caporale, Teresa, Sensi, Stefano L., Parnis, Julia, Nolte, Christiane, Fishman, Daniel, Shoshan-Barmatz, Varda, Herrmann, Sharon, Khananshvili, Daniel, Sekler, Israel
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806722/
https://ncbi.nlm.nih.gov/pubmed/20018762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908099107
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