EGFR Inhibition Abrogates Leiomyosarcoma Cell Chemoresistance through Inactivation of Survival Pathways and Impairment of CSC Potential

BACKGROUND: Tumor cells with stem-like phenotype and properties, known as cancer stem cells (CSC), have been identified in most solid tumors and are presumed to be responsible for driving tumor initiation, chemoresistance, relapse, or metastasis. A subpopulation of cells with increased stem-like pot...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Sette, Giovanni, Salvati, Valentina, Memeo, Lorenzo, Fecchi, Katia, Colarossi, Cristina, Di Matteo, Paola, Signore, Michele, Biffoni, Mauro, D’Andrea, Vito, De Antoni, Enrico, Canzonieri, Vincenzo, De Maria, Ruggero, Eramo, Adriana
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2012
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466184/
https://ncbi.nlm.nih.gov/pubmed/23056514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046891
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