EGFR Inhibition Abrogates Leiomyosarcoma Cell Chemoresistance through Inactivation of Survival Pathways and Impairment of CSC Potential

BACKGROUND: Tumor cells with stem-like phenotype and properties, known as cancer stem cells (CSC), have been identified in most solid tumors and are presumed to be responsible for driving tumor initiation, chemoresistance, relapse, or metastasis. A subpopulation of cells with increased stem-like pot...

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Detaylı Bibliyografya
Asıl Yazarlar: Sette, Giovanni, Salvati, Valentina, Memeo, Lorenzo, Fecchi, Katia, Colarossi, Cristina, Di Matteo, Paola, Signore, Michele, Biffoni, Mauro, D’Andrea, Vito, De Antoni, Enrico, Canzonieri, Vincenzo, De Maria, Ruggero, Eramo, Adriana
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466184/
https://ncbi.nlm.nih.gov/pubmed/23056514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046891
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