Tyr1068-phosphorylated epidermal growth factor receptor (EGFR) predicts cancer stem cell targeting by erlotinib in preclinical models of wild-type EGFR lung cancer

Tyrosine kinase inhibitors (TKIs) have shown strong activity against non-small-cell lung cancer (NSCLC) patients harboring activating epidermal growth factor receptor (EGFR) mutations. However, a fraction of EGFR wild-type (WT) patients may have an improvement in terms of response rate and progressi...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Sette, G, Salvati, V, Mottolese, M, Visca, P, Gallo, E, Fecchi, K, Pilozzi, E, Duranti, E, Policicchio, E, Tartaglia, M, Milella, M, De Maria, R, Eramo, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558509/
https://ncbi.nlm.nih.gov/pubmed/26247735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.217
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