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Noscapine targets EGFR(p-Tyr1068) to suppress the proliferation and invasion of MG63 cells
Osteosarcoma, the most common primary malignant bone tumor, usually arises in the metaphysis of long bones. Amplification and mutation of the epidermal growth factor receptor (EGFR) gene represent signature genetic abnormalities encountered in osteosarcoma. Noscapine is a benzylisoquinoline alkaloid...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5103267/ https://ncbi.nlm.nih.gov/pubmed/27830833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37062 |
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