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Analysis of Ubiquitin E3 Ligase Activity using selective polyubiquitin binding proteins
The ubiquitin proteasome pathway controls the cellular degradation of ~80–90% of the proteome in a highly regulated manner. In this pathway, E3 ligases are responsible for the conjugation of ubiquitin to protein substrates which can lead to their destruction by the 26S proteasome. Aberrant E3 ligase...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3465502/ https://ncbi.nlm.nih.gov/pubmed/22721718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2012.06.013 |
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