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Controlling synaptotagmin activity by electrostatic screening

Exocytosis of neurosecretory vesicles is mediated bythe SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) proteins syntaxin-1, synaptobrevin, and SNAP-25, with synaptotagmin functioning as the major Ca(2+)-sensor for triggering membrane fusion. Here we show that bovine ch...

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Detalhes bibliográficos
Main Authors: Park, Yongsoo, Hernandez, Javier M., van den Bogaart, Geert, Ahmed, Saheeb, Holt, Matthew, Riedel, Dietmar, Jahn, Reinhard
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465474/
https://ncbi.nlm.nih.gov/pubmed/22940675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2375
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