Cis- and trans-membrane interactions of synaptotagmin-1

In neurotransmission synaptotagmin-1 tethers synaptic vesicles to the presynaptic plasma membrane by binding to acidic membrane lipids and SNAREs and promotes rapid SNARE-mediated fusion upon Ca(2+) triggering. However, recent studies suggested that upon membrane contact synaptotagmin may not only b...

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Main Authors: Vennekate, Wensi, Schröder, Sabrina, Lin, Chao-Chen, van den Bogaart, Geert, Grunwald, Matthias, Jahn, Reinhard, Walla, Peter Jomo
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2012
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390864/
https://ncbi.nlm.nih.gov/pubmed/22711810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1116326109
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