Cas9–crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria

Clustered, regularly interspaced, short palindromic repeats (CRISPR)/CRISPR-associated (Cas) systems provide adaptive immunity against viruses and plasmids in bacteria and archaea. The silencing of invading nucleic acids is executed by ribonucleoprotein complexes preloaded with small, interfering CR...

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Bibliografiska uppgifter
Huvudupphovsmän: Gasiunas, Giedrius, Barrangou, Rodolphe, Horvath, Philippe, Siksnys, Virginijus
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2012
Ämnen:
PNAS Plus
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465414/
https://ncbi.nlm.nih.gov/pubmed/22949671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208507109
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