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Cas9–crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria
Clustered, regularly interspaced, short palindromic repeats (CRISPR)/CRISPR-associated (Cas) systems provide adaptive immunity against viruses and plasmids in bacteria and archaea. The silencing of invading nucleic acids is executed by ribonucleoprotein complexes preloaded with small, interfering CR...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2012
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3465414/ https://ncbi.nlm.nih.gov/pubmed/22949671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208507109 |
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