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In vitro reconstitution of Cascade-mediated CRISPR immunity in Streptococcus thermophilus
Clustered regularly interspaced short palindromic repeats (CRISPR)-encoded immunity in Type I systems relies on the Cascade (CRISPR-associated complex for antiviral defence) ribonucleoprotein complex, which triggers foreign DNA degradation by an accessory Cas3 protein. To establish the mechanism for...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
European Molecular Biology Organization
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3567492/ https://ncbi.nlm.nih.gov/pubmed/23334296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.352 |
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