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Fusion activation by a headless parainfluenza virus 5 hemagglutinin-neuraminidase stalk suggests a modular mechanism for triggering

The Paramyxoviridae family of enveloped viruses enters cells through the concerted action of two viral glycoproteins. The receptor-binding protein, hemagglutinin-neuraminidase (HN), H, or G, binds its cellular receptor and activates the fusion protein, F, which, through an extensive refolding event,...

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Autors principals: Bose, Sayantan, Zokarkar, Aarohi, Welch, Brett D., Leser, George P., Jardetzky, Theodore S., Lamb, Robert A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465404/
https://ncbi.nlm.nih.gov/pubmed/22949640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213813109
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