Structure and Mutagenesis of the Parainfluenza Virus 5 Hemagglutinin-Neuraminidase Stalk Domain Reveals a Four-Helix Bundle and the Role of the Stalk in Fusion Promotion

Paramyxovirus entry into cells requires the fusion protein (F) and a receptor binding protein (hemagglutinin-neuraminidase [HN], H, or G). The multifunctional HN protein of some paramyxoviruses, besides functioning as the receptor (sialic acid) binding protein (hemagglutinin activity) and the recept...

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Bibliographic Details
Main Authors: Bose, Sayantan, Welch, Brett D., Kors, Christopher A., Yuan, Ping, Jardetzky, Theodore S., Lamb, Robert A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2011
Subjects:
Structure and Assembly
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233124/
https://ncbi.nlm.nih.gov/pubmed/21994464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06350-11
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