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Mutagenesis of Paramyxovirus Hemagglutinin-Neuraminidase Membrane-Proximal Stalk Region Influences Stability, Receptor Binding, and Neuraminidase Activity

Paramyxoviridae consist of a large family of enveloped, negative-sense, nonsegmented single-stranded RNA viruses that account for a significant number of human and animal diseases. The fusion process for nearly all paramyxoviruses involves the mixing of the host cell plasma membrane and the virus en...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Adu-Gyamfi, Emmanuel, Kim, Lori S., Jardetzky, Theodore S., Lamb, Robert A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988141/
https://ncbi.nlm.nih.gov/pubmed/27334593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00896-16
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