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Structure of the Newcastle disease virus hemagglutinin-neuraminidase (HN) ectodomain reveals a four-helix bundle stalk

The paramyxovirus hemagglutinin-neuraminidase (HN) protein plays multiple roles in viral entry and egress, including binding to sialic acid receptors, activating the fusion (F) protein to activate membrane fusion and viral entry, and cleaving sialic acid from carbohydrate chains. HN is an oligomeric...

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Detalhes bibliográficos
Main Authors: Yuan, Ping, Swanson, Kurt A., Leser, George P., Paterson, Reay G., Lamb, Robert A., Jardetzky, Theodore S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169104/
https://ncbi.nlm.nih.gov/pubmed/21873198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111691108
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