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T cells engineered with a T cell receptor against the prostate antigen TARP specifically kill HLA-A2(+) prostate and breast cancer cells
To produce genetically engineered T cells directed against prostate and breast cancer cells, we have cloned the T-cell receptor recognizing the HLA-A2–restricted T-cell recptor γ-chain alternate reading-frame protein (TARP)(4–13) epitope. TARP is a protein exclusively expressed in normal prostate ep...
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| Główni autorzy: | , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3465394/ https://ncbi.nlm.nih.gov/pubmed/23019373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209042109 |
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