Treatment with MOG-DNA vaccines induces CD4(+)CD25(+)FoxP3(+) regulatory T cells and up-regulates genes with neuroprotective functions in experimental autoimmune encephalomyelitis

BACKGROUND: DNA vaccines represent promising therapeutic strategies in autoimmune disorders such as multiple sclerosis (MS). However, the precise mechanisms by which DNA vaccines induce immune regulation remain largely unknown. Here, we aimed to expand previous knowledge existing on the mechanisms o...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Fissolo, Nicolás, Costa, Carme, Nurtdinov, Ramil N, Bustamante, Marta F, Llombart, Victor, Mansilla, María J, Espejo, Carmen, Montalban, Xavier, Comabella, Manuel
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2012
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464883/
https://ncbi.nlm.nih.gov/pubmed/22727044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-139
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires