Intradermal vaccination prevents anti-MOG autoimmune encephalomyelitis in macaques

BACKGROUND: Autoimmune demyelinating diseases (ADD) are a major cause of neurological disability due to autoreactive cellular and humoral immune responses against brain antigens. A cure for chronic ADD could be obtained by appropriate immunomodulation. METHODS: We implemented a preclinical scheme to...

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Veröffentlicht in:EBioMedicine
Hauptverfasser: Fovet, Claire-Maëlle, Stimmer, Lev, Contreras, Vanessa, Horellou, Philippe, Hubert, Audrey, Seddiki, Nabila, Chapon, Catherine, Tricot, Sabine, Leroy, Carole, Flament, Julien, Massonneau, Julie, Tchitchek, Nicolas, 't Hart, Bert A., Zurawski, Sandra, Klucar, Peter, Hantraye, Philippe, Deiva, Kumaran, Zurawski, Gerard, Oh, SangKon, Le Grand, Roger, Serguera, Ché
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019
Schlagworte:
Research paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796575/
https://ncbi.nlm.nih.gov/pubmed/31492559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.08.052
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