Anti-MOG autoantibodies pathogenicity in children and macaques demyelinating diseases

BACKGROUND: Autoantibodies against myelin oligodendrocyte glycoprotein (anti-MOG-Abs) occur in a majority of children with acquired demyelinating syndromes (ADS) and physiopathology is still under investigation. As cynomolgus macaques immunized with rhMOG, all develop an experimental autoimmune ence...

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Pubblicato in:J Neuroinflammation
Autori principali: Serguera, Che, Stimmer, Lev, Fovet, Claire-Maelle, Horellou, Philippe, Contreras, Vanessa, Tchitchek, Nicolas, Massonneau, Julie, Leroy, Carole, Perrin, Audrey, Flament, Julien, Hantraye, Philippe, Demilly, Joanna, Marignier, Romain, Chrétien, Pascale, Hart, Bert‘t, Boutonnat, Jean, Adam, Clovis, Le-Grand, Roger, Deiva, Kumaran
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6884758/
https://ncbi.nlm.nih.gov/pubmed/31785610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1637-7
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