Wnt/β-catenin pathway regulates ABCB1 transcription in chronic myeloid leukemia

BACKGROUND: The advanced phases of chronic myeloid leukemia (CML) are known to be more resistant to therapy. This resistance has been associated with the overexpression of ABCB1, which gives rise to the multidrug resistance (MDR) phenomenon. MDR is characterized by resistance to nonrelated drugs, an...

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Bibliografische gegevens
Hoofdauteurs: Corrêa, Stephany, Binato, Renata, Du Rocher, Bárbara, Castelo-Branco, Morgana TL, Pizzatti, Luciana, Abdelhay, Eliana
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2012
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464798/
https://ncbi.nlm.nih.gov/pubmed/22823957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-303
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