Canonical WNT Signaling Pathway is Altered in Mesenchymal Stromal Cells From Acute Myeloid Leukemia Patients And Is Implicated in BMP4 Down-Regulation()

Mesenchymal stromal cells (hMSCs) are key components of the bone marrow microenvironment (BMM). A molecular signature in hMSCs from Acute myeloid leukemia patients (hMSC-AML) has been proposed where BMP4 is decreased and could be regulated by WNT signaling pathway. Therefore, the aim of this work wa...

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Detalhes bibliográficos
Publicado no:Transl Oncol
Main Authors: Azevedo, Pedro L., Oliveira, Nathalia C.A., Corrêa, Stephany, Castelo-Branco, Morgana T.L., Abdelhay, Eliana, Binato, Renata
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2019
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Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6350721/
https://ncbi.nlm.nih.gov/pubmed/30703678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2019.01.003
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