Wnt/β-catenin pathway regulates ABCB1 transcription in chronic myeloid leukemia

BACKGROUND: The advanced phases of chronic myeloid leukemia (CML) are known to be more resistant to therapy. This resistance has been associated with the overexpression of ABCB1, which gives rise to the multidrug resistance (MDR) phenomenon. MDR is characterized by resistance to nonrelated drugs, an...

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Hlavní autoři: Corrêa, Stephany, Binato, Renata, Du Rocher, Bárbara, Castelo-Branco, Morgana TL, Pizzatti, Luciana, Abdelhay, Eliana
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464798/
https://ncbi.nlm.nih.gov/pubmed/22823957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-303
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