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Wnt/β-catenin pathway regulates ABCB1 transcription in chronic myeloid leukemia
BACKGROUND: The advanced phases of chronic myeloid leukemia (CML) are known to be more resistant to therapy. This resistance has been associated with the overexpression of ABCB1, which gives rise to the multidrug resistance (MDR) phenomenon. MDR is characterized by resistance to nonrelated drugs, an...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3464798/ https://ncbi.nlm.nih.gov/pubmed/22823957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-303 |
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