Wnt/β-catenin pathway regulates ABCB1 transcription in chronic myeloid leukemia

BACKGROUND: The advanced phases of chronic myeloid leukemia (CML) are known to be more resistant to therapy. This resistance has been associated with the overexpression of ABCB1, which gives rise to the multidrug resistance (MDR) phenomenon. MDR is characterized by resistance to nonrelated drugs, an...

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Main Authors: Corrêa, Stephany, Binato, Renata, Du Rocher, Bárbara, Castelo-Branco, Morgana TL, Pizzatti, Luciana, Abdelhay, Eliana
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2012
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464798/
https://ncbi.nlm.nih.gov/pubmed/22823957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-303
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