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Deciphering Mode of Action of Heparanase Using Structurally Defined Oligosaccharides

Heparan sulfate (HS) is a highly sulfated polysaccharide that serves many biological functions, including regulating cell growth and inflammatory responses as well as the blood coagulation process. Heparanase is an enzyme that cleaves HS and is known to display a variety of pathophysiological effect...

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Библиографические подробности
Главные авторы: Peterson, Sherket, Liu, Jian
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464585/
https://ncbi.nlm.nih.gov/pubmed/22893710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.390161
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