Molecular Structure of Heparan Sulfate from Spalax: IMPLICATIONS OF HEPARANASE AND HYPOXIA

Spalax, a subterranean blind mole rat, is well adapted to live in an extreme hypoxic environment through up-regulated expression of growth factors and enzymes for ensuring sufficient oxygen supply. One of the overexpressed enzymes is heparanase, an endoglucuronidase that selectively cleaves heparan...

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Bibliographische Detailangaben
Hauptverfasser: Sandwall, Elina, Bodevin, Sabrina, Nasser, Nicola J., Nevo, Eviatar, Avivi, Aaron, Vlodavsky, Israel, Li, Jin-Ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2009
Schlagworte:
Glycobiology and Extracellular Matrices
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2635051/
https://ncbi.nlm.nih.gov/pubmed/19068480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802196200
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