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Alternatively spliced Spalax heparanase inhibits extracellular matrix degradation, tumor growth, and metastasis

Heparanase is an endoglycosidase that degrades heparan sulfate (HS) at the cell surface and in the extracellular matrix. Heparanase is expressed mainly by cancer cells, and its expression is correlated with increased tumor aggressiveness, metastasis, and angiogenesis. Here, we report the cloning of...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Nasser, Nicola J., Avivi, Aaron, Shafat, Itay, Edovitsky, Evgeny, Zcharia, Eyal, Ilan, Neta, Vlodavsky, Israel, Nevo, Eviatar
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2009
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650141/
https://ncbi.nlm.nih.gov/pubmed/19164514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812846106
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