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Deciphering Mode of Action of Heparanase Using Structurally Defined Oligosaccharides

Heparan sulfate (HS) is a highly sulfated polysaccharide that serves many biological functions, including regulating cell growth and inflammatory responses as well as the blood coagulation process. Heparanase is an enzyme that cleaves HS and is known to display a variety of pathophysiological effect...

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Detalhes bibliográficos
Main Authors: Peterson, Sherket, Liu, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464585/
https://ncbi.nlm.nih.gov/pubmed/22893710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.390161
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