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Deciphering Mode of Action of Heparanase Using Structurally Defined Oligosaccharides
Heparan sulfate (HS) is a highly sulfated polysaccharide that serves many biological functions, including regulating cell growth and inflammatory responses as well as the blood coagulation process. Heparanase is an enzyme that cleaves HS and is known to display a variety of pathophysiological effect...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3464585/ https://ncbi.nlm.nih.gov/pubmed/22893710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.390161 |
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