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Polymorphic Fibrillation of the Destabilized Fourth Fasciclin-1 Domain Mutant A546T of the Transforming Growth Factor-β-induced Protein (TGFBIp) Occurs through Multiple Pathways with Different Oligomeric Intermediates
Mutations in the transforming growth factor β-induced protein (TGFBIp) are linked to the development of corneal dystrophies in which abnormal protein deposition in the cornea leads to a loss of corneal transparency and ultimately blindness. Different mutations give rise to phenotypically distinct co...
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Prif Awduron: | , , , , , , |
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Fformat: | Artigo |
Iaith: | Inglês |
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American Society for Biochemistry and Molecular Biology
2012
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Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3464576/ https://ncbi.nlm.nih.gov/pubmed/22893702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.379552 |
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