Focus on molecules: Transforming growth factor beta induced protein (TGFBIp)

por Runager, Kasper, Enghild, Jan J., Klintworth, Gordon K.
Publicado 2007

Targeting O-Glycosyltransferase (OGT) to Promote Healing of Diabetic Skin Wounds

por Runager, Kasper, Bektas, Meryem, Berkowitz, Paula, Rubenstein, David S.
Publicado 2014

The human protein haptoglobin inhibits IsdH-mediated heme-sequestering by Staphylococcus aureus

por Mikkelsen, Jakob H., Runager, Kasper, Andersen, Christian B. F.
Publicado en J Biol Chem (2020)

The insoluble TGFBIp-fraction of the cornea is covalently linked via a disulfide bond to type XII collagen

por Runager, Kasper, Klintworth, Gordon K., Karring, Henrik, Enghild, Jan J.
Publicado 2013

Composition and proteolytic processing of corneal deposits associated with mutations in the TGFBI gene

por Karring, Henrik, Runager, Kasper, Thøgersen, Ida B., Klintworth, Gordon K., Højrup, Peter, Enghild, Jan J.
Publicado 2011

Differential expression and processing of transforming growth factor beta induced protein (TGFBIp) in the normal human cornea during postnatal development and aging

por Karring, Henrik, Runager, Kasper, Valnickova, Zuzana, Thøgersen, Ida B., Møller-Pedersen, Torben, Klintworth, Gordon K., Enghild, Jan J.
Publicado 2009

Polymorphic Fibrillation of the Destabilized Fourth Fasciclin-1 Domain Mutant A546T of the Transforming Growth Factor-β-induced Protein (TGFBIp) Occurs through Multiple Pathways wi...

por Andreasen, Maria, Nielsen, Søren B., Runager, Kasper, Christiansen, Gunna, Nielsen, Niels Chr., Enghild, Jan J., Otzen, Daniel E.
Publicado 2012

Serine protease HtrA1 accumulates in corneal transforming growth factor beta induced protein (TGFBIp) amyloid deposits

por Karring, Henrik, Poulsen, Ebbe Toftgaard, Runager, Kasper, Thøgersen, Ida B., Klintworth, Gordon K., Højrup, Peter, Enghild, Jan J.
Publicado 2013

Purification, crystallization and preliminary X-ray diffraction of wild-type and mutant recombinant human transforming growth factor β-induced protein (TGFBIp)

por Runager, Kasper, García-Castellanos, Raquel, Valnickova, Zuzana, Kristensen, Torsten, Nielsen, Niels Chr., Klintworth, Gordon K., Gomis-Rüth, F. Xavier, Enghild, Jan J.
Publicado 2009

Early Events in the Amyloid Formation of the A546T Mutant of Transforming Growth Factor Beta Induced Protein (TGFBIp) in Corneal Dystrophies Compared to the Non-Fibrillating R555W...

por Koldsø, Heidi, Andersen, Ole Juul, Nikolajsen, Camilla Lund, Scavenius, Carsten, Sørensen, Charlotte S., Underhaug, Jarl, Runager, Kasper, Nielsen, Niels Chr., Enghild, Jan J., Schiøtt, Birgit
Publicado en Biochemistry (2015)

The fibril core of transforming growth factor beta-induced protein (TGFBIp) facilitates aggregation of corneal TGFBIp

por Sørensen, Charlotte S., Runager, Kasper, Scavenius, Carsten, Jensen, Morten M., Nielsen, Nadia S., Christiansen, Gunna, Petersen, Steen V., Karring, Henrik, Sanggaard, Kristian W., Enghild, Jan J.
Publicado en Biochemistry (2015)

Proteomic profiling of TGFBI-null mouse corneas reveals only minor changes in matrix composition supportive of TGFBI knockdown as therapy against TGFBI-linked corneal dystrophies

por Poulsen, Ebbe Toftgaard, Runager, Kasper, Nielsen, Nadia Sukusu, Lukassen, Marie V., Thomsen, Karen, Snider, Paige, Simmons, Olga, Vorum, Henrik, Conway, Simon J., Enghild, Jan J.
Publicado en FEBS J (2017)

Comparison of two phenotypically distinct lattice corneal dystrophies caused by mutations in the transforming growth factor beta induced (TGFBI) gene

por Poulsen, Ebbe Toftgaard, Runager, Kasper, Risør, Michael W., Dyrlund, Thomas F., Scavenius, Carsten, Karring, Henrik, Praetorius, Jeppe, Vorum, Henrik, Otzen, Daniel E., Klintworth, Gordon K., Enghild, Jan J.
Publicado 2014

Mutation in Transforming Growth Factor Beta Induced protein associated with Granular Corneal Dystrophy Type 1 Reduces the Proteolytic Susceptibility through Local Structural Stabil...

por Underhaug, Jarl, Koldsø, Heidi, Runager, Kasper, Nielsen, Jakob Toudahl, Sørensen, Charlotte S., Kristensen, Torsten, Otzen, Daniel E., Karring, Henrik, Malmendal, Anders, Schiøtt, Birgit, Enghild, Jan J., Nielsen, Niels Chr.
Publicado 2013

Proteomics of Fuchs’ Endothelial Corneal Dystrophy Support That the Extracellular Matrix of Descemet’s Membrane Is Disordered

por Poulsen, Ebbe Toftgaard, Dyrlund, Thomas F., Runager, Kasper, Scavenius, Carsten, Krogager, Toke Peter, Højrup, Peter, Thøgersen, Ida B., Sanggaard, Kristian W., Vorum, Henrik, Hjortdal, Jesper, Enghild, Jan J.
Publicado en J Proteome Res (2014)

The serine protease HtrA1 cleaves misfolded transforming growth factor β–induced protein (TGFBIp) and induces amyloid formation

por Poulsen, Ebbe Toftgaard, Nielsen, Nadia Sukusu, Scavenius, Carsten, Mogensen, Emilie Hage, Risør, Michael W., Runager, Kasper, Lukassen, Marie V., Rasmussen, Casper B., Christiansen, Gunna, Richner, Mette, Vorum, Henrik, Enghild, Jan J.
Publicado en J Biol Chem (2019)

Human Phenotypically Distinct TGFBI Corneal Dystrophies Are Linked to the Stability of the Fourth FAS1 Domain of TGFBIp

por Runager, Kasper, Basaiawmoit, Rajiv V., Deva, Taru, Andreasen, Maria, Valnickova, Zuzana, Sørensen, Charlotte S., Karring, Henrik, Thøgersen, Ida B., Christiansen, Gunna, Underhaug, Jarl, Kristensen, Torsten, Nielsen, Niels Chr., Klintworth, Gordon K., Otzen, Daniel E., Enghild, Jan J.
Publicado 2011