Rac1 drives melanoblast organization during mouse development by orchestrating pseudopod-driven motility and cell cycle progression

During embryogenesis, melanoblasts proliferate and migrate ventrally through the developing dermis and epidermis as single cells. Targeted deletion of Rac1 in melanoblasts during embryogenesis causes defects in migration, cell cycle progression and cytokinesis. Rac1 null cells migrate markedly less...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Li, Ang, Ma, Yafeng, Yu, Xinzi, Mort, Richard L., Lindsay, Colin, Stevenson, David, Strathdee, Douglas, Insall, Robert H., Chernoff, Jonathan, Snapper, Scott B., Jackson, Ian J., Larue, Lionel, Sansom, Owen J., Machesky, Laura M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464460/
https://ncbi.nlm.nih.gov/pubmed/21924960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.07.008
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi