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Anti-HIV Double Variable Domain Immunoglobulins Binding Both gp41 and gp120 for Targeted Delivery of Immunoconjugates

BACKGROUND: Anti-HIV immunoconjugates targeted to the HIV envelope protein may be used to eradicate the latent reservoir of HIV infection using activate-and-purge protocols. Previous studies have identified the two target epitopes most effective for the delivery of cytotoxic immunoconjugates the CD4...

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Bibliografiske detaljer
Main Authors: Craig, Ryan B., Summa, Christopher M., Corti, Miriam, Pincus, Seth H.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464217/
https://ncbi.nlm.nih.gov/pubmed/23056448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046778
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