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Random Field Model Reveals Structure of the Protein Recombinational Landscape

We are interested in how intragenic recombination contributes to the evolution of proteins and how this mechanism complements and enhances the diversity generated by random mutation. Experiments have revealed that proteins are highly tolerant to recombination with homologous sequences (mutation by r...

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Detalhes bibliográficos
Main Authors: Romero, Philip A., Arnold, Frances H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464211/
https://ncbi.nlm.nih.gov/pubmed/23055915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002713
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