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Large granular lymphocyte leukemia: from dysregulated pathways to therapeutic targets
Large granular lymphocyte (LGL) leukemia is a clonal lymphoproliferative disorder of cytotoxic lymphocytes characterized by an expansion of CD3(+) cytotoxic T lymphocytes or CD3(−) natural killer cells. Patients present with various cytopenias including neutropenia, anemia and thrombocytopenia. In a...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3464048/ https://ncbi.nlm.nih.gov/pubmed/22830400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fon.12.75 |
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