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Large granular lymphocyte leukemia: from dysregulated pathways to therapeutic targets

Large granular lymphocyte (LGL) leukemia is a clonal lymphoproliferative disorder of cytotoxic lymphocytes characterized by an expansion of CD3(+) cytotoxic T lymphocytes or CD3(−) natural killer cells. Patients present with various cytopenias including neutropenia, anemia and thrombocytopenia. In a...

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Bibliografische gegevens
Hoofdauteurs: LeBlanc, Francis, Zhang, Dan, Liu, Xin, Loughran, Thomas P
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464048/
https://ncbi.nlm.nih.gov/pubmed/22830400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fon.12.75
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