Δ-9,11 Modification of Glucocorticoids Dissociates Nuclear Factor-κB Inhibitory Efficacy from Glucocorticoid Response Element-Associated Side Effects

Glucocorticoids are standard of care for many inflammatory conditions, but chronic use is associated with a broad array of side effects. This has led to a search for dissociative glucocorticoids—drugs able to retain or improve efficacy associated with transrepression [nuclear factor-κB (NF-κB) inhib...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Baudy, Andreas R., Reeves, Erica K. M., Damsker, Jesse M., Heier, Christopher, Garvin, Lindsay M., Dillingham, Blythe C., McCall, John, Rayavarapu, Sree, Wang, Zuyi, Vandermeulen, Jack H., Sali, Arpana, Jahnke, Vanessa, Duguez, Stephanie, DuBois, Debra, Rose, Mary C., Nagaraju, Kanneboyina, Hoffman, Eric P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Pharmacology and Experimental Therapeutics 2012
Gaiak:
Cellular and Molecular
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464029/
https://ncbi.nlm.nih.gov/pubmed/22743576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.194340
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak