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The Cochaperone Shutdown Defines a Group of Biogenesis Factors Essential for All piRNA Populations in Drosophila

In animal gonads, PIWI proteins and their bound 23–30 nt piRNAs guard genome integrity by the sequence specific silencing of transposons. Two branches of piRNA biogenesis, namely primary processing and ping-pong amplification, have been proposed. Despite an overall conceptual understanding of piRNA...

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Hlavní autoři: Olivieri, Daniel, Senti, Kirsten-André, Subramanian, Sailakshmi, Sachidanandam, Ravi, Brennecke, Julius
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463805/
https://ncbi.nlm.nih.gov/pubmed/22902557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.07.021
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