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The piRNA Pathway: Guardian of the Genome –A Fly’s Perspective

Throughout the eukaryotic lineage, small RNA silencing pathways protect the genome against the deleterious influence of selfish genetic elements such as transposons. In animals an elaborate small RNA pathway centered on PIWI proteins and their interacting piRNAs silences transposons within the germl...

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Detalles Bibliográficos
Publicado en:Trends Genet
Main Authors: Senti, Kirsten-André, Brennecke, Julius
Formato: Artigo
Idioma:Inglês
Publicado: 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988489/
https://ncbi.nlm.nih.gov/pubmed/20934772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2010.08.007
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