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Molecular Pathways: Context-dependent approaches to Notch targeting as cancer therapy

Recent high throughput genomic sequencing studies of solid tumors, including head and neck squamous cell carcinoma (SCC), ovarian cancer, lung adenocarcinoma, glioblastoma, breast cancer and lung SCC, have highlighted DNA mutation as a mechanism for aberrant Notch signaling. A primary challenge of t...

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書誌詳細
主要な著者: Egloff, Ann Marie, Grandis, Jennifer R.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463728/
https://ncbi.nlm.nih.gov/pubmed/22773520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-2258
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